Th2:extracellular Th2:extracellular 1.0 -1.0 IFNG 1.0 -1.0 IL33 Th2:membrane Th2:membrane 1.0 -1.0 IFNGR1; IFNGR2 1.0 -1.0 IL1RL1 1.0 -1.0 IL1RAP 1.0 -1.0 CD28 1.0 -1.0 CD4 1.0 -1.0 HLA-DMA;HLA-DMB;HLA-DOA;HLA-DOB;HLA-DPA1; HLA-DPB1;HLA-DPB2;HLA-DQA1;HLA-DQA2; HLA-DQB1;HLA-DQB2;HLA-DQB3;HLA-DRA; HLA-DRB1;HLA-DRB3;HLA-DRB4;HLA-DRB5;LOC100509457 1.0 -1.0 CD80 1.0 -1.0 CD86 1.0 -1.0 LAT 1.0 -1.0 TRAC;TRAJ18;TRAV24; TRB;TRBV11-1;TRBV11-2; TRBV11-3;TRBV17 Th2:cytosol Th2:cytosol 1.0 -1.0 **ATM/ART regulation of G1/S checkpoint 1.0 -1.0 **Cell cycle regulation 1.0 -1.0 **Regulation of EIF2 activity 1.0 -1.0 **Regulation of translation 1.0 -1.0 **Regulation of EIF4F activity 1.0 -1.0 *1,2-Diacyglycerol 1.0 -1.0 PRKCA 1.0 -1.0 PRKCD 1.0 -1.0 AFAP1 1.0 -1.0 SRC 1.0 -1.0 AKT1; AKT2; AKT3 1.0 -1.0 RAPGEF1 1.0 -1.0 RAP1A 1.0 -1.0 *Ca('2+) 1.0 -1.0 CALM1; CALM2; CALM3 1.0 -1.0 CAMK2A; CAMK2B;CAMK2D; CAMK2G 1.0 -1.0 CRKL 1.0 -1.0 MAPK1; MAPK3 1.0 -1.0 FANCC 1.0 -1.0 ICAM1 1.0 -1.0 **Cell adhesion 1.0 -1.0 JAK1 1.0 -1.0 JAK2 1.0 -1.0 MAP3K1 1.0 -1.0 CBL 1.0 -1.0 *IP3 1.0 -1.0 SOCS1 1.0 -1.0 EIF2AK2 1.0 -1.0 CDKN1A 1.0 -1.0 PLCG2 1.0 -1.0 PTK2B 1.0 -1.0 MAP2K1; MAP2K2 1.0 -1.0 MAP2K6 1.0 -1.0 MAPK14; MAPK11;MAPK13; MAPK12 1.0 -1.0 MAP3K4 1.0 -1.0 PDPK1 1.0 -1.0 PIK3CA; PIK3CB; PIK3CD 1.0 -1.0 *PtdIns(3,4,5)P3 1.0 -1.0 PIK3R1; PIK3R2; PIK3R3 1.0 -1.0 *PtdIns(4,5)P2 1.0 -1.0 **Inhibition of cell proliferation 1.0 -1.0 PTPN11 1.0 -1.0 **TGF-beta receptor signaling 1.0 -1.0 **GM-CSF signalling 1.0 -1.0 **Inflammatory response 1.0 -1.0 **IL-13 signaling via JAK-STAT 1.0 -1.0 **IL-13 signaling via PI3K-ERK 1.0 -1.0 **IL-5 signalling 1.0 -1.0 **IL-6 signalling pathway 1.0 -1.0 **IL-8 dependent cell migration and adhesion 1.0 -1.0 **Inhibitory action of Lipoxins on pro-inflammatory TNF-alpha signalling 1.0 -1.0 NOS3 1.0 -1.0 CCL2 1.0 -1.0 SELE 1.0 -1.0 RPS6KA5 1.0 -1.0 CSF2 1.0 -1.0 CXCL1 1.0 -1.0 H2AFX;H2AFZ;HIST1H2AC; HIST1H2AD;HIST1H2AG;HIST1H2AI; HIST1H2AJ;HIST1H2AK;HIST1H2AL; HIST1H2AM;HIST2H2AC 1.0 -1.0 H2BFS;HIST1H2BB;HIST1H2BC;HIST1H2BD; HIST1H2BE;HIST1H2BF;HIST1H2BG;HIST1H2BH; HIST1H2BI;HIST1H2BJ;HIST1H2BL;HIST1H2BM; HIST1H2BN;HIST1H2BO;HIST2H2BE;LOC102724334 1.0 -1.0 IKBKB; CHUK 1.0 -1.0 IKBKG 1.0 -1.0 IL13 1.0 -1.0 IL17F 1.0 -1.0 IL5 1.0 -1.0 IL6 1.0 -1.0 CXCL8 1.0 -1.0 MYD88 1.0 -1.0 IRAK1 1.0 -1.0 TRAF6 1.0 -1.0 IRAK4 1.0 -1.0 MAPK10; MAPK8; MAPK9 1.0 -1.0 MAP2K3 1.0 -1.0 MAP2K4 1.0 -1.0 MAP2K7 1.0 -1.0 *N-omega- Hydroxy- L-arginine 1.0 -1.0 *L-Citrulline 1.0 -1.0 *NO 1.0 -1.0 TNF 1.0 -1.0 VCAM1 1.0 -1.0 MAP3K14 1.0 -1.0 **Angiogenesis 1.0 -1.0 TMED1 1.0 -1.0 TAB1 1.0 -1.0 MAP3K7 1.0 -1.0 TAB2 1.0 -1.0 UBB;UBC 1.0 -1.0 **Regulation of actin cytoskeleton by Rho GTPases 1.0 -1.0 **Cytoskeleton remodeling 1.0 -1.0 PRKCQ 1.0 -1.0 BCL10 1.0 -1.0 UBE2N 1.0 -1.0 MALT1 1.0 -1.0 CARD11 1.0 -1.0 GRAP2 1.0 -1.0 GRB2 1.0 -1.0 ITK 1.0 -1.0 CD247; CD3D;CD3E; CD3G 1.0 -1.0 ZAP70 1.0 -1.0 LCK 1.0 -1.0 LCP2 1.0 -1.0 PLCG1 1.0 -1.0 UBE2V2 1.0 -1.0 RAC1 1.0 -1.0 VAV1 Th2:endoplasmic reticulum Th2:endoplasmic reticulum 1.0 -1.0 *Ca('2+) 1.0 -1.0 ITPR1; ITPR2; ITPR3 Th2:nucleus Th2:nucleus 1.0 -1.0 BRCA1 1.0 -1.0 STAT1; IRF9;STAT2 1.0 -1.0 CEBPB 1.0 -1.0 CREBBP 1.0 -1.0 IRF1 1.0 -1.0 SMAD7 1.0 -1.0 MYC 1.0 -1.0 MCM5 1.0 -1.0 EP300 1.0 -1.0 ATF2 1.0 -1.0 NFKBIA; NFKBIB; NFKBIE 1.0 -1.0 RELA;REL; NFKB1;RELB; NFKB2 1.0 -1.0 JUN