Eosinophil:extracellular Eosinophil:extracellular 1.0 -1.0 CCL13 1.0 -1.0 CCL5 1.0 -1.0 CCL7 1.0 -1.0 CCL8 1.0 -1.0 CCL11 1.0 -1.0 CCL24 1.0 -1.0 CCL26 1.0 -1.0 **Trans-endothelial immune cell migration 1.0 -1.0 **Immune response 1.0 -1.0 CCL17 1.0 -1.0 CCL22 1.0 -1.0 **Allergic inflammation 1.0 -1.0 **Asthma 1.0 -1.0 **Atopic dermatitis (AD) 1.0 -1.0 **T cell chemotaxis to lung 1.0 -1.0 **T cell chemotaxis to skin 1.0 -1.0 IL3 1.0 -1.0 IL5 Eosinophil:membrane Eosinophil:membrane 1.0 -1.0 CCR3 1.0 -1.0 CYBA; CYBB 1.0 -1.0 CCR4 1.0 -1.0 ITGB2; ITGAL 1.0 -1.0 ITGA4; ITGB1 1.0 -1.0 IL3RA; IL5RA; CSF2RB 1.0 -1.0 ICAM1 1.0 -1.0 ITGAM Eosinophil:cytosol Eosinophil:cytosol 1.0 -1.0 **Prostaglandin 2 "biosynthesis and metabolism FM 1.0 -1.0 **Inflammatory response 1.0 -1.0 **Reactive oxygen species production 1.0 -1.0 *1,2-Diacyglycerol 1.0 -1.0 PRKCA 1.0 -1.0 *1-Palmitoyl- 2-arachidonyl- 3-sn-phosphatidylcholine 1.0 -1.0 *1-Palmitoyl- 3-sn- phosphatidylcholine 1.0 -1.0 *Arachidonic acid 1.0 -1.0 ACTB; ACTG1 1.0 -1.0 **Actomyosin structure organization 1.0 -1.0 ACTR2;ACTR3;ACTR3B; ARPC1A;ARPC1B; ARPC2;ARPC3;ARPC4; ARPC4-TTLL3;ARPC5 1.0 -1.0 FGR 1.0 -1.0 GNAI1;GNAI2; GNAI3;GNAO1; GNAZ 1.0 -1.0 GNB1;GNB2;GNB3;GNB4;GNB5; GNG10;GNG11;GNG12;GNG13; GNG2;GNG3;GNG4;GNG5;GNG7; GNG8;GNGT1;GNGT2 1.0 -1.0 HCK 1.0 -1.0 *Ca('2+) 1.0 -1.0 **NF-AT signaling and leukocyte interactions 1.0 -1.0 CALM1; CALM2; CALM3 1.0 -1.0 PLA2G4A; PLA2G4C 1.0 -1.0 MYLK; MYLK2; MYLK3 1.0 -1.0 CFL1; CFL2 1.0 -1.0 *O(,2)('-) 1.0 -1.0 DIAPH1 1.0 -1.0 PFN2; PFN1 1.0 -1.0 MAPK1; MAPK3 1.0 -1.0 WAS 1.0 -1.0 SRC 1.0 -1.0 PIK3CG 1.0 -1.0 PIK3R5 1.0 -1.0 PLCB2 1.0 -1.0 HRAS 1.0 -1.0 RAF1 1.0 -1.0 *IP3 1.0 -1.0 *L-Arginine 1.0 -1.0 *L-Citrulline 1.0 -1.0 *NO 1.0 -1.0 LIMK2 1.0 -1.0 MAP2K1 1.0 -1.0 MAP2K2 1.0 -1.0 MAP2K4 1.0 -1.0 MAPK11;MAPK12; MAPK13;MAPK14 1.0 -1.0 MAP3K1 1.0 -1.0 MYL1;MYL3; MYL4;MYL6; MYL6B 1.0 -1.0 MYH1;MYH10;MYH11;MYH13; MYH14;MYH15;MYH16; MYH2;MYH3;MYH4;MYH6; MYH7;MYH8;MYH9 1.0 -1.0 MYL12A;MYL12B; MYL2;MYL5;MYL7; MYL9;MYLPF 1.0 -1.0 PPP1CB 1.0 -1.0 PPP1R12A 1.0 -1.0 *O(,2) 1.0 -1.0 PAK1 1.0 -1.0 NCF1 1.0 -1.0 PDPK1 1.0 -1.0 PRKCZ 1.0 -1.0 *PtdIns(3,4,5)P3 1.0 -1.0 *PtdIns(4,5)P2 1.0 -1.0 ROCK2; ROCK1 1.0 -1.0 RAC1 1.0 -1.0 NCF2 1.0 -1.0 RAC2 1.0 -1.0 NOS2 1.0 -1.0 RHOA 1.0 -1.0 TIAM1 1.0 -1.0 VAV2 1.0 -1.0 RASGRP2 1.0 -1.0 PRKCD 1.0 -1.0 RAP1A 1.0 -1.0 CYTH1 1.0 -1.0 PLCB3 1.0 -1.0 PIP5K1C 1.0 -1.0 *Phosphatidylinositol 4-phosphate 1.0 -1.0 TLN1; TLN2 1.0 -1.0 RASSF5 1.0 -1.0 **T cell receptor signaling 1.0 -1.0 PPP3CA; PPP3CB; PPP3CC 1.0 -1.0 FOSB;ATF2;JUND; JUN;FOSL2;JUNB; FOSL1;FOS 1.0 -1.0 CISH 1.0 -1.0 JAK2 1.0 -1.0 GRB2 1.0 -1.0 SOS1; SOS2 1.0 -1.0 SHC1 1.0 -1.0 PIM1 1.0 -1.0 SOCS1 1.0 -1.0 SOCS3 1.0 -1.0 INPP5D 1.0 -1.0 PTPN11 1.0 -1.0 PTPN6 1.0 -1.0 ID1 1.0 -1.0 OSM 1.0 -1.0 **AKT signaling 1.0 -1.0 **Anti-apoptosis 1.0 -1.0 **Regulation of Apoptosis by Mithochondrial proteins 1.0 -1.0 *CoA 1.0 -1.0 *Platelet activating factor 1.0 -1.0 AKT1; AKT2; AKT3 1.0 -1.0 *Acetyl-CoA 1.0 -1.0 RAPGEF1 1.0 -1.0 CRKL 1.0 -1.0 CCND3 1.0 -1.0 **Eosinophil adhesion 1.0 -1.0 JAK1 1.0 -1.0 LYN 1.0 -1.0 SYK 1.0 -1.0 LPCAT2 1.0 -1.0 PIK3R1; "PIK3R2 1.0 -1.0 PIK3CA; PIK3CB; PIK3CD 1.0 -1.0 **Oxidative stress 1.0 -1.0 **Cell differentiation Eosinophil:endoplasmic reticulum Eosinophil:endoplasmic reticulum 1.0 -1.0 ITPR1; ITPR2; ITPR3 1.0 -1.0 *Ca('2+) Eosinophil:mitochondria Eosinophil:mitochondria 1.0 -1.0 BCL2 Eosinophil:nucleus Eosinophil:nucleus 1.0 -1.0 STAT5A; STAT5B 1.0 -1.0 NFATC2 1.0 -1.0 EGR1 1.0 -1.0 ELF1 1.0 -1.0 ELK1 1.0 -1.0 FOS;ATF2;FOSB; JUN;FOSL1;JUND; FOSL2;JUNB 1.0 -1.0 POU2F1 1.0 -1.0 STAT1 1.0 -1.0 STAT3 1.0 -1.0 BTK 1.0 -1.0 MYC Th2:cytosol Th2:cytosol 1.0 -1.0 **NF-AT signaling and leukocytes interaction 1.0 -1.0 **Th1 and Th2 cell differentiation endothelial:membrane endothelial:membrane 1.0 -1.0 ICAM1 1.0 -1.0 VCAM1